California Detox Clinics

Alpha Recovery Center in Lancaster, California offers medically supervised drug and alcohol detoxification with 24/7 monitoring, followed by residential inpatient and outpatient levels of care. The evidence-based program treats substance use and co-occurring mental health disorders, and accepts most major insurance plans.

The Ranch is Ranch Recovery Centers, Inc.'s men's residential campus in Desert Hot Springs, in operation since 1972. It houses up to 43 men in dormitory settings within an organization that also runs Hacienda Valdez for women and a family program, and lists several commercial insurers plus Medi-Cal information.

Mending Bridges has provided substance use and co-occurring mental health treatment in Orange County, California since 2014, running a full continuum from medically supervised alcohol and drug detox through residential inpatient care to partial hospitalization and intensive outpatient programming. Its detox is delivered in a dedicated house, PHP gives intensive structure without an overnight stay, and IOP is for people living at home who need support around work or family. The approach is trauma-informed and holistic, and the program is licensed by the California Department of Health Care Services (license 300779BP, expiring October 2026). Private and military insurance are accepted, and it works with most major insurers.

Design for Change is a JCAHO-accredited drug and alcohol rehab on East Avenue J in Lancaster, California, where the provider says its program has run for more than 20 years with a deliberately low client-to-staff ratio. Care begins with sub-acute detox and continues into a 30-day residential track, with co-occurring mental health treatment, a family program and post-treatment support; a second Lancaster site operates on 16th Street West. Private insurance and self-pay are accepted, including plans from Aetna, Cigna, Blue Cross Blue Shield, Anthem, Kaiser Permanente, Humana, Magellan, Health Net, TRICARE and ComPsych.

Rebel New Life Treatment Center in Anaheim, California provides detoxification and residential treatment for men and women, combining faith-centered support with evidence-based clinical care. The center embraces a client-centered approach addressing the whole person — mind, body, and spirit — with individualized treatment plans that include experiential therapies and community building. Rebel New Life is listed with SAMHSA and Psychology Today.

Phoenix House Orange County provides long-term residential treatment, withdrawal management, intensive outpatient and outpatient care for substance use disorders in Santa Ana, California, as part of the non-profit Phoenix House network. The program accepts Medi-Cal — California's Medicaid program — alongside private and military insurance, and offers state-funded places, public assistance and a sliding scale for clients paying themselves.

California Behavioral Health provides drug and alcohol rehab in Palm Springs and Cathedral City, California. The program offers residential treatment and outpatient programming with a structured admissions process and aftercare planning. CBH publishes patient outcome data and maintains several professional accreditations.

Advanced Therapeutic Services is an outpatient addiction and mental health treatment center in Rancho Mirage, California. It offers intensive outpatient and partial hospitalization programs for adults with co-occurring conditions, and lists commercial insurers including Anthem Blue Cross, Aetna, Cigna, and TRICARE.

Sierra Health and Wellness Centers provides residential treatment and outpatient addiction and mental health care in Northern California. The program offers medically supervised detoxification, residential inpatient care, and intensive outpatient (IOP) levels, treating substance use disorders alongside co-occurring mental health conditions such as PTSD — with a specialized understanding of veterans and first responders. Sierra Health accepts Medicaid, Medicare, TRICARE, and most private insurance plans. Same-day assessments are available, and the program coordinates family involvement and aftercare planning.

Door to Hope is a non-profit residential substance use treatment program for women in Salinas, California, with withdrawal management on site. It works with adult and young adult women, including those with co-occurring mental health conditions. Medicaid and Medicare are accepted, alongside private and military insurance and self-pay.

Inland Valley Recovery Services (IVRS) has provided substance abuse recovery and counseling in Upland, California since 1962, serving roughly 4,000 people a year. Its continuum includes residential and inpatient treatment, detoxification, outpatient and intensive outpatient programs, and perinatal services, with bilingual English/Spanish staff. IVRS is a nonprofit agency that accepts most private health insurance, including Aetna, Cigna, Anthem, UnitedHealthcare and Meritain.

Serenity Cottages of the Desert is a men's residential addiction treatment center near Baker, California, deep in the Mojave Desert and a long way from anywhere — which is the point of the setting. Medical detox is the first stage, with medication-assisted treatment available, and the program combines conventional therapy with yoga, meditation and art therapy. Private and military insurance and self-pay are accepted, and the center works with carriers including Kaiser Permanente, Health Net, Cigna, Aetna, Blue Cross, United Healthcare and TRICARE.

Tarzana Treatment Centers is a behavioral health provider founded in 1972 and accredited by The Joint Commission, with an Antelope Valley location serving Palmdale and Lancaster, California. The Palmdale program offers outpatient substance use treatment, medication-assisted treatment (MAT), withdrawal management (detox), and dedicated services for veterans and active-duty service members, and accepts Medicare, Medicaid and private insurance.

The Loma Linda University Behavioral Medicine Center, part of Loma Linda University Health, provides inpatient and outpatient treatment for mental illness and substance use disorders in Redlands, CA. Its specialized programs include a Substance Use Recovery and Wellness Program, adult and youth partial hospitalization and intensive outpatient programs, and outpatient therapy. The center accepts Medicaid, private insurance, and military insurance including TRICARE.

Pacific Sands Recovery Center is a boutique detox and residential addiction treatment facility in Santa Ana, Orange County, offering just six beds — four in private rooms — for individualized care. The program treats drug and alcohol addiction, dual diagnosis, and complex medical conditions, with services including medically supervised detox, residential treatment, medication-assisted treatment, and 12-step programming. Licensed by the California Department of Health Care Services and JCAHO accredited, Pacific Sands also offers a dedicated rehab track for veterans. The facility accepts major insurance plans including Anthem Blue Cross, Aetna, TRICARE, TriWest, GEHA, Magellan, and Carelon.

Merito House is a residential addiction treatment home on Church Street in Redlands, part of the His House New Creation network across San Bernardino County. Treatment is Christian and faith-based, and the network runs gender-specific facilities so men and women are treated separately, with detox, residential inpatient, intensive outpatient and sober living all available within it. His House holds Joint Commission accreditation and is licensed and certified by the California Department of Health Care Services. Medicaid, Medicare, private and military insurance, state funding and self-pay are accepted.

Present Moments Recovery is a CARF-accredited, DHCS-licensed provider whose detox and residential programs run at its San Marcos location, with PHP, IOP and medication-assisted treatment continuing at a Carlsbad clinic under what it describes as one connected clinical team. The provider reports more than ten years in practice, treats opioid and fentanyl use alongside co-occurring conditions, and uses naltrexone or Vivitrol where clinically appropriate. Private insurance is accepted, including Cigna, Blue Cross Blue Shield, Anthem, TRICARE and TriWest; the center states on its own site that it does not accept Medicare or Medi-Cal.