Text Size
Smaller
Bigger

Can long term tramadol permanently deplete my serotonin?

answered 10:47 PM EST, Fri January 10, 2014
-- filed under:
anonymous anonymous
I am 4 and a half weeks out of a 3 year Tramadol habit. I went cold turkey which was a bad idea. I was feeling pretty depressed for a while but that is slowly lifting but I still feel less positive than normal. Is there anything I can do to speed up the PAWS from tramadol? Do diets that are supposed to increase serotonin levels really make any difference? Could a long time use of tramadol permanently deplete my serotonin levels to a point where I would need to us an SSRI just to get back to baseline?

Dr. Stuart Shipko Says...

Most people are surprised to learn that depression is not caused by a 'chemical imbalance' related to serotonin or any other neurotransmitter.  Actually, the chemical imbalance concept was originally a marketing strategy.  Chemical imbalances aside, depression that people experience when stopping opiates can sometimes be severe and may be associated with suicidality.  You describe a significant depression that has already improved.  Sometimes with severe withdrawal depression an antidepressant is needed.  If your depression has improved significantly the antidepressant is not needed.  I typically avoid prescribing any medications when people withdraw from medications because over time the prescribed medication may well become a problem.  When patients have mild to moderate depression I often recommend a supplement, SAM-e at a 400 mg daily dosage along with b-complex.  This facilitates synthesis of neurotransmitters and has a proven track record in helping depression.  

 
Email It Send this page Print It Print friendly page Subscribe Subscribe to this topic category

Page last updated Jan 10, 2014

Call Now for
Rehab Options
Insurance Accepted
(Except Medicare)

Join Thousands of Readers

who receive our weekly recovery newsletter.

Addictions: Featured Experts
All Experts

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.